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Location ID: 0502,0401,EN

Bioscience and Engineering - Bioscience Cource

Bioscience and Engineering

About Bioscience and Engineering

In the bioscience course, the mechanisms of genetics and aging are elucidated through biotechnology, yielding solutions. Research efforts are directed toward the needs of an aging society, seeking out the causes of dementia due to aging and developing means of preventing it, for example, so that everyone can lead fulfilling lives in their later years.

Research Domain

Biotechnology, biology, pharmacology, genetics, cells, microorganisms, environment, aging, dementia, hormones, proteins, enzymes, immunity, organic synthesis, bacteria, global environment, physiology, biopolymers, food hygiene

What is aging? -The elucidation of the mechanism on neuronal aging-

Molecular Cell Biology Laboratory

Koji Fukui

Our research is based on the free radical theory of aging. This famous theory is proposed by D. Harman in 1950s. Reactive oxygen species (ROS) attack living tissues and induce oxidative deterioration. The oxidative damage accelerates the risk of the development and progression of serious neurodegenerative diseases such as Alzheimer’s and Parkinson’s. In these severe diseases, neuronal cell death occur in the brain. In order to prevent ROS-related neuronal cell death, we are focusing on the event before induction of neuronal cell death. We found neurite degeneration before induction of cell death in vivo and in vitro models. Furthermore, we found microtubule destabilization and autophagy alteration. Recently, we have assessed the mechanism of Alzheimer’s disease using transgenic models. We are continuing to research the relationship between oxidative damage and neurodegenerative disorders.

Lab. Detail Head of Lab. Keyword
Biological Polymer Lab. Detail Kenichi Iwata microbiology, enzymology, DNA cloning, protein expression, protein purification, X-ray analysis
Food and Nutrition Lab. Detail Naomi Osakabe polyphenol, neuroscience, biochemistry, metabolic syndrome, locomotive syndrome, cognitive function
SciVal Profile Tadashi Shinkai  
Laboratory of Organic Synthesis and Medicinal Chemistry Detail Yoshitomo Suhara organic synthesis, medicinal chemistry, vitamin K, collagen mimic, carbohydrate
SciVal Profile Yoshihisa Hirota  
Molecular Cell Biology Laboratory Detail Koji Fukui Oxidative Stress, Antioxidant, Neurodegeneration, Aging
SciVal Profile Hiroyuki Fuse  

A major issue facing society in the 21st Century is that of maintaining a healthy lifestyle and cultural activities. A number of avenues are being explored to address this and include, establishing a series of preventative methods, treatments, and rehabilitation services for diseases that afflict the elderly such as cancer, circulatory diseases, and diabetes, as well as developing a preventative and control system of degenerative conditions present in the elderly. In other words, it is of importance to build an active society involving the elderly, and healthy ageing by exploiting scientific knowledge. Therefore, the Department is structured to foster individuals having a systematic approach in the comprehension of life, medical care, and welfare. The Department exposes students to understand the complexities of life, life phenomenon, and individual living functions, thereby having a greater insight into age-associated healthy living.

The research activities involve an understanding of the pathogenic mechanisms of ageing-associated degenerative changes that have yet to be understood thoroughly, and establish preventative methods based on scientific findings and diagnosis methods for biological dysfunctions developing with the onset of disease. Additionally, R&D is conducted towards medical and welfare apparatus, including advanced systems and methods that will allow for recovery from the onset of biological dysfunctions or control the condition.

Life forms are born and grown on this earth, reach maturity, and then age, gradually changing their physiology and motor functions. These changes generally appear more as old age sets in, but in some theories the process of being born and grown is seen as a part of aging. An immortality drug has been a constant dream of humanity, but such a thing can never be. Rather, we are in an era where we need to focus on growing old healthily.
In the Department of Bioscience and Engineering, we tackle the mysteries of life head-on by using biotechnology to scientifically explain human aging through physiological explanations, the effects of drugs and food, environmental causes, microorganisms, and match them with basic research and the development of devices that are based on engineering methods such as artificial organs, regenerative medicine, medical robots, assistive devices, and rehabilitation methods.
The Department of Bioscience and Engineering allows students to select their major from two distinctive courses. The Bioscience Course is based on biotechnology, and the Biomedical Engineering Course is based on creating mechanical and electrical devices. Both courses are paired with instruction in the foundations of bioscience, such as biotechnology, bioinformatics, biological functions, genes, regenerative medicine, welfare support, and life support as joint core subjects. The fusion of these two courses allows us to offer multi-disciplinary research and education.

Bioscience Course
This course focuses on scientific explanations and solutions for an unavoidable phenomena of life that are genes and aging, based on biotechnology, pharmacology, and biology. Our research fields include microbiology, biochemistry, pharmacology, drug synthesis chemistry, physiology, protein enzymes, food and nutrition, and environmental science.

The Department of Bioscience and Engineering welcomes applicants who understand the features and educational content described above, and are willing to boldly tackle the mysteries of the human bodies and the riddles of life, or who desire to create things to help society.

The graduates are highly sought after for wide-range chemical engineering industries, specifically, foods, medicine, medical, pharmaceutical, and biotechnology-related firms. Employment opportunities are not only limited to researcher and engineering professions, and include product and technology sales, MR (medical representative), and new product development/planning. It is also recommended that graduates progress towards post-graduate studies to further strengthen their expertise.